"sister chromatid exchanges and micronuclei in lymphocyte of nurses handling antineoplastic drugs"
نویسندگان
چکیده
individuals handling antineoplastic drugs or their wastes may absorb these potent genotoxic agents. the effects of handling antineoplastic drugs were examined in a group of 24 nurses working in the hematology and oncology departments of two different university hospitals in shiraz (iran) and in a group of 18 unexposed nurses as control group. the cytogenetic repercussions of exposure were assessed by examining sister chromatid exchanges (sces) and micronuclei (mn) in circulating lymphocytes. a significant increased frequencies of sce and mn is observed in circulating lymphocytes. a significant increased frequencies of sce and mn is observed in nurses in daily contact with antineoplastic drugs as compared to control group.
منابع مشابه
hematological changes in nurses handling antineoplastic drugs
a cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). the control group, matched by sex, and age, consisted of 18 nurses, worked on other sect...
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عنوان ژورنال:
iranian journal of public healthجلد ۳۰، شماره ۱-۲، صفحات ۳۷-۴۰
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